Clinical Context Peer-reviewed veterinary literature continues to shape everyday decision-making for canine patients, especially when new evidence clarifies diagnosis, treatment selection, monitoring, or clinical outcomes.

What the Study Evaluated A study published in Journal of veterinary internal medicine in 2026 evaluated correlation of urine ammonia excretion with renal function in healthy dogs and dogs with chronic kidney disease..

Key Findings Inadequate ammonia excretion is thought to drive the development of metabolic acidosis in people with chronic kidney disease (CKD) and correlates with worse clinical outcomes, such as faster progression to end-stage kidney disease and increased case fatality. To determine if urine ammonia-to-creatinine ratio (UACR) correlates with serum creatinine concentration as a renal function marker in healthy dogs and dogs with CKD and whether UACR…