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The addition of clotrimazole reduces but does not abrogate fungal dysbiosis during effective antibacterial therapy for canine otitis externa.
Clinical evidence update from The Journal of small animal practice
Clinical Context Peer-reviewed veterinary literature continues to shape everyday decision-making for canine patients, especially when new evidence clarifies diagnosis, treatment selection, monitoring, or clinical outcomes.
What the Study Evaluated A study published in The Journal of small animal practice in 2026 evaluated the addition of clotrimazole reduces but does not abrogate fungal dysbiosis during effective antibacterial therapy for canine otitis externa..
Key Findings Malassezia dysbiosis commonly occurs after successful piperacillin-tazobactam monotherapy for canine bacterial otitis externa. The study objective was to compare antimicrobial outcomes in dogs with otitis treated with piperacillin-tazobactam in combination with the antifungal drug clotrimazole with a previous cohort treated with piperacillin-tazobactam alone. Twenty-one dogs with bacterial otitis were treated top…
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