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Article · Clinical Study · 2 min read

Efficacy of non-steroidal anti-inflammatory drug (NSAID) treatment for bovine respiratory disease: a systematic review and meta-analysis for the European Network for Optimization of Antimicrobial Therapy guidelines.

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Clinical evidence update from Open research Europe

May 22, 2026 at 12:00 PM UTCOpen research EuropeVeterinary33 Editorial Desk

Comments on this article are also part of the Veterinary33 clinical forum.

Efficacy of non-steroidal anti-inflammatory drug (NSAID) treatment for bovine respiratory disease: a systematic review and meta-analysis for the European Network for Optimization of Antimicrobial Therapy guidelines.

Clinical Context

Peer-reviewed veterinary literature continues to shape everyday decision-making for production animal practice, especially when new evidence clarifies diagnosis, treatment selection, monitoring, or clinical outcomes.

What the Study Evaluated

A study published in Open research Europe in 2026 evaluated efficacy of non-steroidal anti-inflammatory drug (NSAID) treatment for bovine respiratory disease: a systematic review and meta-analysis for the European Network for Optimization of Antimicrobial Therapy guidelines..

Key Findings

Non-steroidal anti-inflammatory drugs (NSAIDs) are widely used as ancillary therapy for bovine respiratory disease (BRD) alongside antimicrobials, and interest in NSAID monotherapy has grown amid antimicrobial stewardship and welfare concerns. We evaluated the clinical effectiveness of NSAIDs for BRD as adjunctive or sole therapy. We conducted a systematic review and meta-analysis of randomized controlled trials (RCTs) in cattle with naturally occurring BRD. Databases searched were MEDLINE (Ovid), Embase (Ovid), CAB Abstracts (Ovid), Biological Abstracts (Ovid), Web of Science Core Collection, and Scopus (search: 22 Apr 2024; update: 12 Sep...

Why It Matters for Veterinary Professionals

For veterinary professionals, the practical value of this work lies in how the findings may support more structured clinical assessment, clearer monitoring, and more informed decisions for production animal practice.

Practical Interpretation

The results should be interpreted in the context of the study design, population, inclusion criteria, and clinical setting. Application in practice should consider patient-specific risk factors, available diagnostics, local standards of care, and clinician judgment.

Clinical Takeaway

Overall, the study adds useful evidence for clinicians seeking to align daily practice with current veterinary research while maintaining a balanced, case-by-case approach.

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